Growth retardation in children receiving long-term total parenteral nutrition: effects of ornithine alpha-ketoglutarate.

@article{Moukarzel1994GrowthRI,
  title={Growth retardation in children receiving long-term total parenteral nutrition: effects of ornithine alpha-ketoglutarate.},
  author={Adib A Moukarzel and Olivier Goulet and Jordi S Salas and C Mart{\'i}-henneberg and Alan L. Buchman and Luc A Cynober and Raphael Rappaport and Claude C Ricour},
  journal={The American journal of clinical nutrition},
  year={1994},
  volume={60 3},
  pages={408-13}
}
We evaluated the effect of ornithine ketoglutarate (OKG) in reversing abnormal growth in six prepubertal children receiving total parenteral nutrition (TPN) for 5-10 y. They were 1-4 SDs below their expected 50th percentile for height. The energy and nitrogen intakes were unchanged from 8 mo before the beginning of the study until its completion. Two consecutive periods of 5 mo each were studied. OKG (15 g) was added to the parenteral solution during the first period (OKG+) but not during the… CONTINUE READING