Growth requirements for avian γδ T cells include exogenous cytokines, receptor ligation and in vivo priming

@inproceedings{Kasahara1993GrowthRF,
  title={Growth requirements for avian γδ T cells include exogenous cytokines, receptor ligation and in vivo priming},
  author={Yoshihito Kasahara and Chris. Chen and Max D. Cooper},
  year={1993}
}
These studies analyze growth requirements for the normal γδ T cell population in peripheral lymphoid tissues. Avian γδ T cells can respond well to T cell mitogens in the presence of αβ T cells, but our studies indicate that they do not grow well alone. Exogenous growth factors were required in order for γδ T cells to proliferate in response to receptor ligation by anti-T cell receptor antibodies or other T cell mitogens. Interleukin-2 was implicated as one of the necessary growth factors that… CONTINUE READING