Growth requirements for avian γδ T cells include exogenous cytokines, receptor ligation and in vivo priming

@article{Kasahara1993GrowthRF,
  title={Growth requirements for avian γδ T cells include exogenous cytokines, receptor ligation and in vivo priming},
  author={Y. Kasahara and C. Chen and M. Cooper},
  journal={European Journal of Immunology},
  year={1993},
  volume={23}
}
  • Y. Kasahara, C. Chen, M. Cooper
  • Published 1993
  • Biology
  • European Journal of Immunology
  • These studies analyze growth requirements for the normal γδ T cell population in peripheral lymphoid tissues. Avian γδ T cells can respond well to T cell mitogens in the presence of αβ T cells, but our studies indicate that they do not grow well alone. Exogenous growth factors were required in order for γδ T cells to proliferate in response to receptor ligation by anti‐T cell receptor antibodies or other T cell mitogens. Interleukin‐2 was implicated as one of the necessary growth factors that… CONTINUE READING
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