Growth rate of vestibular schwannoma

@article{Paldor2016GrowthRO,
  title={Growth rate of vestibular schwannoma},
  author={Iddo Paldor and Annie S. Chen and Andrew H. Kaye},
  journal={Journal of Clinical Neuroscience},
  year={2016},
  volume={32},
  pages={1-8}
}

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References

SHOWING 1-10 OF 47 REFERENCES
Predictors of Vestibular Schwannoma Growth and Clinical Implications
TLDR
Assessment of tumor size at diagnosis and for the presence of tinnitus may allow for risk stratification of patients with newly diagnosed vestibular schwannomas and for a more rational application of the conservative management approach.
Growth Characteristics of Vestibular Schwannomas
  • D. Moffat, A. Kasbekar, P. Axon, S. Lloyd
  • Medicine
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • 2012
TLDR
Tumor growth is usually slow and is most likely to occur within the first 3 years of observation, but growth may occur after five years of follow-up.
Expectant management of vestibular schwannoma: a retrospective multivariate analysis of tumor growth and outcome.
TLDR
No growth within 5 years of surveillance does not guarantee a continued indolent growth pattern; surveillance must therefore continue.
Conservative management of 386 cases of unilateral vestibular schwannoma: tumor growth and consequences for treatment.
TLDR
The results of this study support the role of a conservative "wait-and-scan" policy of management for small-sized vestibular schwannomas because most have a slow growth rate.
Vestibular schwannoma of oscillating size: A case report and review of literature
TLDR
The long-term follow-up of an unusual cystic schwannoma with growth patterns prior to and following treatment, adding valuable information to the variable natural history and outcome of these infrequent tumors.
A Protocol for the Conservative Management of Vestibular Schwannomas
TLDR
A protocol for the safe surveillance of vestibular schwannomas is devised, recommending an initial magnetic resonance imaging scan at 6 months, with scans to take place at annual intervals for 2 years, and a further scan 2 years later will identify any patient with indolent tumors.
Conservative Management of Vestibular Schwannoma: Expectations Based on the Length of the Observation Period
TLDR
For patients electing an observation approach to treatment of a vestibular schwannoma, about 31% may eventually undergo further treatment, however, some patients are followed with radiologic evaluations for many years without necessity for further treatment.
Growth of untreated vestibular schwannoma: a prospective study.
TLDR
Based on the actual measurements, VDT was the most correct way to describe VS growth, and none of the investigated baseline predictors were usable as predictors of growth.
Conservative management of acoustic neuroma.
TLDR
Few patients with small tumors will come to surgery in the short term, so long-term follow-up studies of 20 years or more are required to be come more confident about the natural history of these tumors.
...
...