Growth properties of artificial heterogeneous human colon tumors.

  title={Growth properties of artificial heterogeneous human colon tumors.},
  author={John T. Leith and S. G. Michelson and L E Faulkner and Steve Bliven},
  journal={Cancer research},
  volume={47 4},
Two clonal cell lines (designated as clones A and D), originally isolated from the heterogeneous DLD-1 human colon adenocarcinoma, were used to produce xenograft tumors in nude mice. Neoplasms produced from either A or D cells alone were compared to those produced from a range of percentage admixtures of the two subpopulations. Then, Gompertzian growth parameters (initial growth rates, retardation rates) were determined, along with estimation of the final asymptotic volumes. It was found that… CONTINUE READING


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