Growth on glucose decreases cAMP-CRP activity while paradoxically increasing intracellular cAMP in the light-organ symbiont Vibrio fischeri.

@article{Colton2015GrowthOG,
  title={Growth on glucose decreases cAMP-CRP activity while paradoxically increasing intracellular cAMP in the light-organ symbiont Vibrio fischeri.},
  author={Deanna M. Colton and Julie L Stoudenmire and Eric V. Stabb},
  journal={Molecular microbiology},
  year={2015},
  volume={97 6},
  pages={1114-27}
}
Proteobacteria often co-ordinate responses to carbon sources using CRP and the second messenger cyclic 3', 5'-AMP (cAMP), which combine to control transcription of genes during growth on non-glucose substrates as part of the catabolite-repression response. Here we show that cAMP-CRP is active and important in Vibrio fischeri during colonization of its host… CONTINUE READING