Growth of the small airways and alveoli from childhood to the adult lung measured by aerosol-derived airway morphometry.

@article{Zeman2006GrowthOT,
  title={Growth of the small airways and alveoli from childhood to the adult lung measured by aerosol-derived airway morphometry.},
  author={Kirby L. Zeman and William D. Bennett},
  journal={Journal of applied physiology},
  year={2006},
  volume={100 3},
  pages={
          965-71
        }
}
Understanding the human development of pulmonary air spaces is important for calculating the dose from exposure to inhaled materials as a function of age. We have measured, in vivo, the air space caliber of the small airways and alveoli at their natural full distension [total lung capacity (TLC)] by aerosol-derived airway morphometry in 53 children of age 6-22 yr and 59 adults of age 23-80 yr. Aerosol-derived airway morphometry utilizes the gravitational settling time of inhaled inert particles… 
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