Growth of the flat bones of the membranous neurocranium: A computational model

  title={Growth of the flat bones of the membranous neurocranium: A computational model},
  author={D. A. Garz{\'o}n-Alvarado and Andres Gonz{\'a}lez and Mar{\'i}a Lucia Guti{\'e}rrez},
  journal={Computer methods and programs in biomedicine},
  volume={112 3},
This article assumes two stages in the formation of the bones in the calvaria, the first one takes into account the formation of the primary centers of ossification. This step counts on the differentiation from mesenchymal cells into osteoblasts. A molecular mechanism is used based on a system of reaction-diffusion between two antagonistic molecules, which are BMP2 and Noggin. To this effect we used equations whose behavior allows finding Turing patterns that determine the location of the… CONTINUE READING


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