Growth of immature articular cartilage in vitro: correlated variation in tensile biomechanical and collagen network properties.

@article{Williamson2003GrowthOI,
  title={Growth of immature articular cartilage in vitro: correlated variation in tensile biomechanical and collagen network properties.},
  author={Amanda K Williamson and Koichi Masuda and Eugene J-M A Thonar and Robert L. Sah},
  journal={Tissue engineering},
  year={2003},
  volume={9 4},
  pages={625-34}
}
Articular cartilage biochemical composition and mechanical properties evolve during in utero and in vivo growth, with marked differences between fetus, newborn, and young adult. The objectives of this study were to test whether in vitro growth of bovine fetal and newborn calf articular cartilage explants resulted in changes in biochemical and tensile properties during up to 6 weeks of free-swelling culture in serum-supplemented medium. During this culture period, both fetal and calf cartilage… CONTINUE READING