Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides

@article{Otto2007GrowthOH,
  title={Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides},
  author={Christoph Otto and Ulrike Kaemmerer and Bertram Illert and Bettina Muehling and Nadja Pfetzer and Rainer Wittig and Hans Ullrich Voelker and Arnulf Thiede and Johannes F. Coy},
  journal={BMC Cancer},
  year={2007},
  volume={8},
  pages={122 - 122}
}
Among the most prominent metabolic alterations in cancer cells are the increase in glucose consumption and the conversion of glucose to lactic acid via the reduction of pyruvate even in the presence of oxygen. This phenomenon, known as aerobic glycolysis or the Warburg effect, may provide a rationale for therapeutic strategies that inhibit tumour growth by administration of a ketogenic diet with average protein but low in carbohydrates and high in fat enriched with omega-3 fatty acids and… CONTINUE READING
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