Growth of Mycobacterium avium in human monocytes: identification of cytokines which reduce and enhance intracellular microbial growth.

@article{Denis1991GrowthOM,
  title={Growth of Mycobacterium avium in human monocytes: identification of cytokines which reduce and enhance intracellular microbial growth.},
  author={Michel Denis},
  journal={European journal of immunology},
  year={1991},
  volume={21 2},
  pages={391-5}
}
  • Michel Denis
  • Published 1991 in European journal of immunology
Human monocytes were isolated by standard procedures and their ability to harbor growth of two virulent strains of Mycobacterium avium, TMC724 and TMC7479, was assessed in the absence or presence of cytokines. Both strains of mycobacteria, especially the M. avium TMC7479, grew progressively in untreated human monocytes. Inclusion of certain macrophage-activating cytokines, such as interferon-gamma in the presence of indomethacin or 1.25(OH2)-vitamin D3 (calcitriol) led to significant reductions… CONTINUE READING

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