Growth inhibitory in vitro effects of glycyrrhizic acid in U251 glioblastoma cell line

@article{Li2014GrowthII,
  title={Growth inhibitory in vitro effects of glycyrrhizic acid in U251 glioblastoma cell line},
  author={Song Li and Jian-hong Zhu and Li-ping Cao and Qing Sun and Huan-dong Liu and Wei-De Li and Jinsong Li and Chunhua Hang},
  journal={Neurological Sciences},
  year={2014},
  volume={35},
  pages={1115-1120}
}
Despite dramatic advances in cancer therapy, the overall prognosis of glioblastoma (GBM) remains dismal. Nuclear factor kappa-B (NF-κB) has been previously demonstrated to be constitutively activated in glioblastoma, and it was suggested as a potential therapeutic target. Glycyrrhizic acid (GA) has been proved to have cytotoxic effects in many cancer cell lines. However, its role in glioblastoma has not yet been addressed. Therefore, this study aimed to investigate the effects of GA on human… CONTINUE READING

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