Growth-inhibitory effects of curcumin on ovary cancer cells and its mechanisms.

  title={Growth-inhibitory effects of curcumin on ovary cancer cells and its mechanisms.},
  author={Li-duan Zheng and Qiangsong Tong and Cuihuan Wu},
  journal={Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban},
  volume={24 1},
To study the growth-inhibitory effects of curcumin on human ovary cancer A2780 cells in vitro and its molecular mechanisms, the growth inhibition rates of A2780 cancer cells, after being treated with 10 micromol/L-50 micromol/L curcumin for 6-24 h, were examined by MTT method. The morphological changes of cancer cells were observed under inversion microscopy. Cellular apoptotic rates were determined by using TUNEL. The protein expression levels of bcl-2, p53 and MDM2 in cancer cells were… CONTINUE READING


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