Growth inhibitory and cytotoxic effects of melatonin and its metabolites on human tumour cell lines in vitro.

Abstract

It has been shown in a number of experimental studies that the pineal gland and, more specifically, the pineal indole hormone melatonin, can modulate tumour growth. Most of these resports (for example, Narita & Kudo, 1985; Regelson & Pierpaoli, 1987) refer to experimentally induced mammary carcinomas in rodents. Interestingly, while tumour growth inhibition… (More)
DOI: 10.1038/bjc.1989.272

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