Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68

@inproceedings{Ehrig2012GrowthIO,
  title={Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68},
  author={Klaas Ehrig and Mehmet Okyay Kilinc and Nanhai George Chen and Jochen Stritzker and Lisa Buckel and Qian Zhang and Aladar A. Szalay},
  booktitle={Journal of Translational Medicine},
  year={2012}
}
Despite availability of efficient treatment regimens for early stage colorectal cancer, treatment regimens for late stage colorectal cancer are generally not effective and thus need improvement. Oncolytic virotherapy using replication-competent vaccinia virus (VACV) strains is a promising new strategy for therapy of a variety of human cancers. Oncolytic efficacy of replication-competent vaccinia virus GLV-1h68 was analyzed in both, cell cultures and subcutaneous xenograft tumor models. In this… CONTINUE READING
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