Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor.

@article{Bromberg2010GrowthIA,
  title={Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor.},
  author={Nat{\'a}lia Bromberg and Juliana Luporini Dreyfuss and Caio Vin{\'i}cius Saito Regatieri and Marcelly V. Palladino and Nelson Dur{\'a}n and Helena B. Nader and Marcela Haun and Giselle Zenker Justo},
  journal={Chemico-biological interactions},
  year={2010},
  volume={186 1},
  pages={43-52}
}
The continuing threat to biodiversity lends urgency to the need of identification of sustainable source of natural products. This is not so much trouble if there is a microbial source of the compound. Herein, violacein, a natural indolic pigment extracted from Chromobacterium violaceum, was evaluated for its antitumoral potential against the Ehrlich ascites tumor (EAT) in vivo and in vitro. Evaluation of violacein cytotoxicity using different endpoints indicated that EAT cells were twofold (IC… CONTINUE READING

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