Growth hormone treatment improves body composition in adults with Prader-Willi syndrome.

@article{Hybye2003GrowthHT,
  title={Growth hormone treatment improves body composition in adults with Prader-Willi syndrome.},
  author={Charlotte H{\"o}ybye and Agneta M Hilding and Hans Jacobsson and Marja Thor{\'e}n},
  journal={Clinical endocrinology},
  year={2003},
  volume={58 5},
  pages={653-61}
}
OBJECTIVE Low growth hormone (GH) secretion and hypogonadism are common in patients with Prader-Willi syndrome (PWS). In this study we present the effects of GH treatment on body composition and metabolism in adults with PWS. PATIENTS AND MEASUREMENTS Nineteen patients with clinical PWS were recruited, 13 had PWS genotype. They were randomised to treatment with placebo or GH (Genotropin, Pharmacia Corporation, Sweden) 0.8 IU (0.2 mg) daily for 1 month and then 1.6 IU (0.5 mg) daily for 5… CONTINUE READING

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