Growth hormone treatment and risk of second neoplasms in the childhood cancer survivor.

@article{ErgunLongmire2006GrowthHT,
  title={Growth hormone treatment and risk of second neoplasms in the childhood cancer survivor.},
  author={Berrin Ergun-Longmire and Ann C Mertens and Pauline A Mitby and Jing Qin and Glenn Heller and W Shi and Yutaka Yasui and Leslie L. Robison and Charles A. Sklar},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 9},
  pages={3494-8}
}
CONTEXT GH deficiency is common in childhood cancer survivors. In a previous report, although we did not find an increase in the risk of disease recurrence in survivors treated with GH, GH-treated survivors did have an increased risk of developing a second neoplasm (SN) (rate ratio, 3.21). OBJECTIVE In this analysis, we have reassessed the risk of GH-treated survivors developing an SN after an additional 32 months of follow-up. DESIGN AND SETTING We conducted a retrospective cohort… CONTINUE READING