Growth hormone therapy in children with CKD after more than two decades of practice

  title={Growth hormone therapy in children with CKD after more than two decades of practice},
  author={Lesley Rees},
  journal={Pediatric Nephrology},
This review focuses on the evidence for the efficacy and safety of recombinant human growth hormone (rhGH) therapy in children with all stages of chronic kidney disease (CKD) and at all ages. It describes the improving height prognosis for our patients both with and without rhGH; explains the underlying hormonal abnormalities that provide the rationale for rhGH use in CKD and the endocrine changes that accompany treatment; and views on who warrants treatment, with what dose, and how long for. 
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