Growth hormone-releasing hormone is produced by adipocytes and regulates lipolysis through growth hormone receptor

@article{RodrguezPacheco2017GrowthHH,
  title={Growth hormone-releasing hormone is produced by adipocytes and regulates lipolysis through growth hormone receptor},
  author={Francisca Rodr{\'i}guez-Pacheco and Carolina Guti{\'e}rrez-Repiso and Sara Garc{\'i}a-Serrano and Ailec Ho-Plagaro and Juan Miguel G{\'o}mez-Zumaquero and Sara Vald{\'e}s and Montserrat Gonzalo and Jose Rivas-Becerra and Custodia Montiel-Casado and Gemma Rojo-Mart{\'i}nez and Eva Garc{\'i}a-Escobar and Eduardo Garc{\'i}a-Fuentes},
  journal={International Journal of Obesity},
  year={2017},
  volume={41},
  pages={1547-1555}
}
Background:Growth hormone-releasing hormone (GHRH) has a crucial role in growth hormone (GH) secretion, but little is known about its production by adipocytes and its involvement in adipocyte metabolism.Objectives:To determine whether GHRH and its receptor (GHRH-R) are present in human adipocytes and to study their levels in obesity. Also, to analyze the effects of GHRH on human adipocyte differentiation and lipolysis.Methods:GHRH/GHRH-R and GH/GH-R mRNA expression levels were analyzed in human… CONTINUE READING