Growth hormone-releasing hormone and extra-pituitary tumorigenesis: therapeutic and diagnostic applications of growth hormone-releasing hormone antagonists.

@article{Kiaris2003GrowthHH,
  title={Growth hormone-releasing hormone and extra-pituitary tumorigenesis: therapeutic and diagnostic applications of growth hormone-releasing hormone antagonists.},
  author={Hippokratis Kiaris and Michael Koutsilieris and Anastasios Th Kalofoutis and Andrew V Schally},
  journal={Expert opinion on investigational drugs},
  year={2003},
  volume={12 8},
  pages={1385-94}
}
Growth hormone-releasing hormone (GHRH) regulates growth hormone release from the pituitary. However, in addition to this neuroendocrine action, much evidence implies an additional role for GHRH in carcinogenesis in non-pituitary tissues. This role of GHRH in cancer development appears to be due to the operation of several mechanisms, which involve the… CONTINUE READING