Growth hormone-releasing hormone: not only a neurohormone

  title={Growth hormone-releasing hormone: not only a neurohormone},
  author={H. Kiaris and I. Chatzistamou and A. Papavassiliou and A. Schally},
  journal={Trends in Endocrinology & Metabolism},
  • H. Kiaris, I. Chatzistamou, +1 author A. Schally
  • Published 2011
  • Biology, Medicine
  • Trends in Endocrinology & Metabolism
  • Growth hormone-releasing hormone (GHRH) is mostly thought to act by stimulating the production and release of growth hormone from the pituitary. However, this neuropeptide emerges as a rather pleiotropic hormone in view of the identification of various extrapituitary sources for GHRH production, as well as the demonstration of a direct action of GHRH on several tissues other than the pituitary. Non-pituitary GHRH has a wide spectrum of activity, exemplified by its ability to modulate cell… CONTINUE READING
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