Growth hormone inhibits its own secretion by acting on the hypothalamus through its receptors on neuropeptide Y neurons in the arcuate nucleus and somatostatin neurons in the periventricular nucleus.

@article{Minami1998GrowthHI,
  title={Growth hormone inhibits its own secretion by acting on the hypothalamus through its receptors on neuropeptide Y neurons in the arcuate nucleus and somatostatin neurons in the periventricular nucleus.},
  author={Shiro Minami and Jun Kamegai and Hitoshi Sugihara and Noriko Suzuki and Ichiji Wakabayashi},
  journal={Endocrine journal},
  year={1998},
  volume={45 Suppl},
  pages={S19-26}
}
GH secretion is regulated by hypothalamic somatostatin and GH-releasing factor. It has been postulated that GH feeds back on the hypothalamus and regulates its own secretion. We focused our attention on the action of GH in the hypothalamus in relation to GH secretion. Adult male rats were used throughout the studies, and the observation was made in conscious rats. Systemic administration of human GH induced c-fos gene expression, a marker of neuronal activity, in the hypothalamic arcuate… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Putative GH pulse renewal: periventricular somatostatinergic control of an arcuate-nuclear somatostatin and GH-releasing hormone oscillator.

American journal of physiology. Regulatory, integrative and comparative physiology • 2004
View 8 Excerpts
Highly Influenced

Actions of NPY, and its Y1 and Y2 receptors on pulsatile growth hormone secretion during the fed and fasted state.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2014
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Similar Papers

Loading similar papers…