Growth hormone increases the collagen deposition rate and breaking strength of left colonic anastomoses in rats.

@article{Christensen1994GrowthHI,
  title={Growth hormone increases the collagen deposition rate and breaking strength of left colonic anastomoses in rats.},
  author={Henrik B rbak Christensen and H R Witek Oxlund},
  journal={Surgery},
  year={1994},
  volume={116 3},
  pages={550-6}
}
BACKGROUND The purpose was to investigate how growth hormone exerts its stimulating effect on the healing of experimental colonic anastomoses. METHODS Rats were treated with biosynthetic growth hormone (bGH); the anastomotic breaking strength, collagen content, and collagen deposition rate (labeling of collagen with 14C-proline) were compared to saline treated controls. RESULTS bGH increased the breaking strength when the rats were treated before and after the operation and when bGH… CONTINUE READING

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