Growth hormone increases circulating neutrophil activation and provokes lung microvascular injury in septic peritonitis rats.

BACKGROUND Growth hormone (GH) has been shown to increase mortality in critical illness, illustrating the need for better understanding of GH treatment. The neutrophil is a key mediator in producing organ injury following shock and trauma and is regulated by GH. Therefore, the purpose of the present study was to examine the effects of GH on circulating… (More)