Growth hormone in obesity

@article{Scacchi1999GrowthHI,
  title={Growth hormone in obesity},
  author={Massimo Scacchi and Angela Ida Pincelli and Francesco Cavagnini},
  journal={International Journal of Obesity},
  year={1999},
  volume={23},
  pages={260-271}
}
Growth hormone (GH) secretion, either spontaneous or evoked by provocative stimuli, is markedly blunted in obesity. In fact obese patients display, compared to normal weight subjects, a reduced half-life, frequency of secretory episodes and daily production rate of the hormone. Furthermore, in these patients GH secretion is impaired in response to all traditional pharmacological stimuli acting at the hypothalamus (insulin-induced hypoglycaemia, arginine, galanin, L-dopa, clonidine, acute… CONTINUE READING
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