Growth hormone can decrease muscle damage complication in tibia lengthening by external fixation.

PURPOSE The purpose of this study was to investigate the effects of growth hormone (GH) on muscles during limb lengthening. METHODS Sixty rats underwent tibial lengthening of approximately 30% after a latency period of 4 days, a distraction period of 30 days with a rate of 0.25 mm twice per day, and a consolidation period of 27 days. Recombinant GH was… (More)