Growth hormone as an early embryonic growth and differentiation factor

@article{Sanders2004GrowthHA,
  title={Growth hormone as an early embryonic growth and differentiation factor},
  author={Esmond J. Sanders and Stephen Harvey},
  journal={Anatomy and Embryology},
  year={2004},
  volume={209},
  pages={1-9}
}
In this review we consider the evidence that growth hormone (GH) acts in the embryo as a local growth, differentiation, and cell survival factor. Because both GH and its receptors are present in the early embryo before the functional differentiation of pituitary somatotrophs and before the establishment of a functioning circulatory system, the conditions are such that GH may be a member of the large battery of autocrine/paracrine growth factors that control embryonic development. It has been… Expand
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