Growth hormone and prostate cancer: guilty by association?

  title={Growth hormone and prostate cancer: guilty by association?},
  author={Adda Grimberg and Pinchas Cohen},
  journal={Journal of endocrinological investigation},
  volume={22 5 Suppl},
Recent case-control studies have found a 7-8% increase in the serum levels of insulin-like growth factor (IGF)-I in patients with prostate cancer (CaP), the most frequently diagnosed cancer in men. We hereby review what is currently known about growth hormone (GH) and the IGF axis in CaP, take a closer inspection of the studies published to date reporting IGF-I levels in CaP patients, and derive implications for the future medical management of patients receiving trophic hormone therapies as… CONTINUE READING


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