Growth hormone- and prolactin-binding proteins in mammalian serum.

  title={Growth hormone- and prolactin-binding proteins in mammalian serum.},
  author={Tamar Amit and Ze’ev Hochberg and Michael J. Waters and Ronnie J Barkey},
  volume={131 4},
The present study was undertaken to characterize the species specificity and diversity of lactogenic and somatogenic binding to serum among mammals and to classify GH-binding protein (GH-BP) in this group of species. Animal sera were characterized on the basis of human (h) GH and bovine (b) PRL binding levels, binding specificity toward GHs and PRLs, binding affinity constant (Ka), and the ability of a monoclonal antirabbit GH receptor antibody (MAb-7) to inhibit the binding to serum. Analyses… CONTINUE READING


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