Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging.

@article{Sonntag2005GrowthHA,
  title={Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging.},
  author={William Edmund Sonntag and Melinda M Ramsey and Christy S. Carter},
  journal={Ageing research reviews},
  year={2005},
  volume={4 2},
  pages={195-212}
}
The concept that growth hormone and IGF-1 are required for normal development of the mammalian body and, more recently the brain, is supported by a vast experimental literature. IGF-1 crosses the blood-brain barrier and in recent years, much attention has focused on age-related decreases in serum growth hormone and IGF-1 as potential mechanisms that may influence cognitive function in the elderly. However, interventional studies are needed to establish a definite link between these hormones and… CONTINUE READING