Growth hormone acutely stimulates skeletal muscle but not whole-body protein synthesis in humans.

@article{Fryburg1993GrowthHA,
  title={Growth hormone acutely stimulates skeletal muscle but not whole-body protein synthesis in humans.},
  author={David A. Fryburg and Eugene J. Barrett},
  journal={Metabolism: clinical and experimental},
  year={1993},
  volume={42 9},
  pages={1223-7}
}
In a previous study, a 6-hour local infusion of growth hormone (GH) into the brachial artery of normal subjects stimulated net muscle protein anabolism by augmenting skeletal muscle protein synthesis. In the present study, we examined whether systemically infused GH affects forearm and whole-body protein metabolism. Normal volunteers aged 18 to 24 years (n = 8) were given an 8-hour systemic infusion of 3H-phenylalanine and 14C-leucine. Between 90 and 120 minutes of tracer infusion, basal… CONTINUE READING

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