Growth hormone (GH) action in early embryogenesis: expression of a GH-response gene in sites of GH production and action

@article{Harvey2001GrowthH,
  title={Growth hormone (GH) action in early embryogenesis: expression of a GH-response gene in sites of GH production and action},
  author={Stephen Harvey and Irina Lavelin and Mark Pines},
  journal={Anatomy and Embryology},
  year={2001},
  volume={204},
  pages={503-510}
}
Growth hormone (GH) may act as a local growth factor in early embryonic development, since GH- and GH-receptor (GHR) immunoreactivity is present in all tissues and most cells of embryonic chicks during organogenesis. However, as GHR-immunoreactivity could, alternatively, reflect the presence of GH-binding proteins (GHBPs) rather than authentic receptors linked to signal transduction mechanisms, GHR immunoreactivity may not be indicative of GH target sites. The possibility that GH may act as an… CONTINUE READING

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