Growth factors mobilize CXCR4 low/negative primitive hematopoietic stem/progenitor cells from the bone marrow of nonhuman primates.

Abstract

Abstract The chemokine receptor CXCR4 is expressed by CD34 + hematopoietic stem/progenitor cells (HSC/HPC). Several investigators have suggested that expression of CXCR4 may be an important characteristic of HSC/HPC. We studied the dynamic expression of CXCR4 during growth factor-induced mobilization of HSC in a clinically relevant nonhuman primate model… (More)

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@article{Mahmud2004GrowthFM, title={Growth factors mobilize CXCR4 low/negative primitive hematopoietic stem/progenitor cells from the bone marrow of nonhuman primates.}, author={Nadim Mahmud and Hetal B. Patel and Ronald Hoffman}, journal={Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation}, year={2004}, volume={10 10}, pages={681-90} }