Growth factor regulation of neuronal development.

  title={Growth factor regulation of neuronal development.},
  author={Mark F. Mehler and John A Kessler},
  journal={Developmental neuroscience},
  volume={16 3-4},
Recent experimental investigations have redefined the spectrum of growth factors and developmental signalling pathways that are necessary to orchestrate the growth and differentiation of regional neuronal subpopulations. Gene knockout studies of the classic neurotrophins and their high-affinity tyrosine kinase (Trk) receptors have refined our definition of the cellular mechanisms and target populations of these neuronotrophic factors. Recognition of the significant parallels that exist between… CONTINUE READING


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