Growth factor production by a human megakaryocytic tumor cell line.

@article{Witte1988GrowthFP,
  title={Growth factor production by a human megakaryocytic tumor cell line.},
  author={David P. Witte and Peter J. Stambrook and Estrella S Feliciano and C L Jones and Michael A. Lieberman},
  journal={Journal of cellular physiology},
  year={1988},
  volume={137 1},
  pages={86-94}
}
A recently described human megakaryocytic tumor cell line was analyzed for the presence of growth factor activity and was found to produce large quantities of transforming growth factor beta-like (TGF-beta) and basic fibroblast growth factor-like (bFGF) activities. Growth factor activities were identified using a radioreceptor assay for the TGF-beta-like activity, a heparin-binding assay for the b-FGF-like activity, and a demonstration of distinct biological activities for each type of factor… CONTINUE READING