Growth factor enhancement of peripheral nerve regeneration through a novel synthetic hydrogel tube.

@article{Midha2003GrowthFE,
  title={Growth factor enhancement of peripheral nerve regeneration through a novel synthetic hydrogel tube.},
  author={Rajiv Midha and Catherine A Munro and Paul D Dalton and Charles Tator and Molly S Shoichet},
  journal={Journal of neurosurgery},
  year={2003},
  volume={99 3},
  pages={555-65}
}
OBJECT The authors' long-term goal is repair of peripheral nerve injuries by using synthetic nerve guidance devices that improve both regeneration and functional outcome relative to an autograft. They report the in vitro processing and in vivo application of synthetic hydrogel tubes that are filled with collagen gel impregnated with growth factors. METHODS Poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) (PHEMA-MMA) porous 12-mm-long tubes with an inner diameter of 1.3 mm and an outer… CONTINUE READING

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Use of tubes in peripheral nerve repair.

Neurosurgery clinics of North America • 2001

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