Growth factor dependency and gene expression in preneoplastic mouse mammary epithelial cells.

@article{Medina1993GrowthFD,
  title={Growth factor dependency and gene expression in preneoplastic mouse mammary epithelial cells.},
  author={Daniel J. Medina and Frances S. Kittrell and Carol J. Oborn and Marlene B. Schwartz},
  journal={Cancer research},
  year={1993},
  volume={53 3},
  pages={668-74}
}
The TM preneoplastic mammary outgrowth lines were established in vivo from mammary epithelial cell lines and have been characterized with respect to their tumorigenic, morphological, and functional properties. The TM outgrowth lines were then established as in vitro cell lines. A comparison of the growth factor dependencies of the TM preneoplastic lines and their progenitor cell lines grown in monolayer cell culture indicated that the TM preneoplastic cell lines exhibited a decreased dependence… CONTINUE READING

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