Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders

@inproceedings{Yatsuga2015GrowthDF,
  title={Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders},
  author={Shuichi Yatsuga and Yasunori Fujita and Akiko Ishii and Yoshihiro Fukumoto and Hajime Arahata and Tatsuyuki Kakuma and Toshio Kojima and Masafumi Ito and Masashi Tanaka and Reo Saiki and Yasutoshi Koga},
  booktitle={Annals of neurology},
  year={2015}
}
OBJECTIVE The diagnosis of mitochondrial disorders (MDs) is occasionally difficult because patients often present with solitary, or a combination of, symptoms caused by each organ insufficiency, which may be the result of respiratory chain enzyme deficiency. Growth differentiation factor 15 (GDF-15) has been reported to be elevated in serum of patients with MDs. In this study, we investigated whether GDF-15 is a more useful biomarker for MDs than several conventional biomarkers. METHODS We… CONTINUE READING
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