Growth differences and differential expression analysis of pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH) between the sexes in half-smooth tongue sole Cynoglossus semilaevis.

@article{Ji2011GrowthDA,
  title={Growth differences and differential expression analysis of pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH) between the sexes in half-smooth tongue sole Cynoglossus semilaevis.},
  author={Xiang Shan Ji and Song‐lin Chen and Yunliang Jiang and Tianjun Xu and Jing-feng Yang and Yong-Sheng Tian},
  journal={General and comparative endocrinology},
  year={2011},
  volume={170 1},
  pages={
          99-109
        }
}
Pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH) are regulators of growth hormone secretion. In this article, we examined the difference in growth and mRNA expression of PACAP and GHRH between the sexes in half-smooth tongue sole, an important cultured fish species indicating sexually growth dimorphism in China. Firstly, a significant body weight difference between females and males was first observed at 7 months (P<0.05) and at 18 onths the… Expand
Genomic structure, polymorphism and expression analysis of growth hormone-releasing hormone and pituitary adenylate cyclase activating polypeptide genes in the half-smooth tongue sole (Cynoglossus semilaevis).
  • Q. Ma, S. Liu, +5 authors Q. Tang
  • Biology, Medicine
  • Genetics and molecular research : GMR
  • 2011
TLDR
GHRH and PACAP mRNA were found to be predominantly expressed in the brain; the expression levels were highest in normal males and extra-large male adults, and no significant differences were found between females and males from the Bohai Sea, the Yellow Sea and hatchery samples. Expand
Genomic structure, polymorphism and expression analysis of the growth hormone (GH) gene in female and male Half-smooth tongue sole (Cynoglossus semilaevis).
Growth hormone (GH) is a polypeptide which is an important regulator of development and somatic growth in teleosts, and may be associated with the mechanisms which drive sexual growth dimorphism inExpand
Regulation of somatic growth and gene expression of the GH–IGF system and PRP-PACAP by dietary lipid level in early juveniles of a teleost fish, the pejerrey (Odontesthes bonariensis)
TLDR
The results show for first time in fish a differential response of PRP-PACAP transcripts to dietary manipulations, and confirm the sensitivity of the pejerrey GH–IGF system to changes in diet composition despite the lack of (or in advance to) a clear response of somatic growth. Expand
DNA Methylation of pacap Gene Is Involved in Growth Superiority of Female Half Smooth Tongue Sole (Cynoglossus semilaevis) in Different Salinities
Pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH) play important roles in the GH/IGF growth axis in fishes. To determine whether epigenetic changeExpand
Effects of low salinity on epigenetic changes of growth hormone and growth hormone receptor in half smooth tongue sole (Cynoglossus semilaevis)
TLDR
The data provide an epigenetic mechanism of explicating the sex duality in phenotypic plasticity of growth rate in male and female of C. semilaevis under different salinities. Expand
Molecular characterization of the GHRH/GHRH-R and its effect on GH synthesis and release in orange-spotted grouper (Epinephelus coioides).
TLDR
Results suggest that the newly obtained grouper GHRH was able to stimulate GH synthesis and release, similar to its mammalian counterparts. Expand
Isolation of Growth Hormone-Releasing Hormone and Its Receptor Genes from Scatophagus argus and Their Expression Analyses
TLDR
The findings indicated that E2, rather than Ghrh, plays an important role in up-regulating the expression of gh in female S. argus, which should aid to understand the sexual dimorphism of teleost growth. Expand
Molecular cloning and functional characterization of growth hormone–releasing hormone in Mastacembelus armatus
TLDR
The data indicate that Ghrh is able to activate the GH-IGFs axis in M. armatus and could significantly upregulate the mRNA expression of growth hormone and insulin-like growth factor-1/2 in this study. Expand
Molecular characterization of kiss2 and differential regulation of reproduction-related genes by sex steroids in the hypothalamus of half-smooth tongue sole (Cynoglossus semilaevis).
TLDR
Insight is provided into the role of sex steroids in the reproductive function of Pleuronectiform teleosts by examining the direct actions of estradiol and testosterone on hypothalamic expression of kisspeptin and other key factors involved in Reproductive function of half-smooth tongue sole. Expand
Molecular cloning and dimorphic expression of growth hormone (gh) in female and male spotted scat Scatophagus argus
TLDR
The qRT-PCR analysis demonstrated that females exhibited higher pituitary gh mRNA levels than males at 6, 18, and 30 months, which implies that the sexual growth dimorphism may be ascribable to the gh levels in pituitaries in spotted scat. Expand
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References

SHOWING 1-10 OF 65 REFERENCES
Sequence and expression of cDNA for pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH)-like peptide in catfish
TLDR
The hypothesis that the two mammalian genes encoding GHRH or PACAP originated from a gene duplication between fish and tetrapods is supported by the present findings of similar mRNA organization and pattern of expression for the one fish gene and two mammalian gene. Expand
Sequence and expression of a cDNA encoding both pituitary adenylate cyclase activating polypeptide and growth hormone-releasing hormone in grouper (Epinephelus coioides).
TLDR
The result suggests that PACAP/GHRH had an important role in the development of embryos and larvae, especially in neurula appearance stage, and the report of PACAP / GHRH mRNA expression in eye and gill tissues in fish is provided. Expand
Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family. Functional implication in the regulation of growth hormone secretion.
TLDR
The hypothesis that the respective roles of GHRH and PACAP in the control of GH secretion are totally inverted in phylogenetically distant groups of vertebrates is presented and provides a unique model in which to investigate the structural and functional facets of evolution. Expand
Gender-specific expression of multiple estrogen receptors, growth hormone receptors, insulin-like growth factors and vitellogenins, and effects of 17 beta-estradiol in the male tilapia (Oreochromis mossambicus).
TLDR
The findings suggest that E2 stimulates Vg production primarily through activation of ER alpha and down-regulation of the GH/IGF-I axis, thus shifting energy from somatic growth towards vitellogenesis at the level of the liver. Expand
Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic Acid microarray analysis.
TLDR
It is established that GH-regulated gene expression is the major mechanistic determinant of sexually dimorphic gene expression in the rat liver model. Expand
Pituitary adenylate cyclase-activating polypeptide (PACAP) as a growth hormone (GH)-releasing factor in grass carp. I. Functional coupling of cyclic adenosine 3',5'-monophosphate and Ca2+/calmodulin-dependent signaling pathways in PACAP-induced GH secretion and GH gene expression in grass carp pitui
TLDR
The results suggest that PACAP stimulates GH synthesis and secretion in grass carp pituitary cells through PAC(1) receptors, mediated by the adenylate cyclase/cAMP/protein kinase A pathway coupled to Ca(2+) entry via VSCC and subsequent activation of CaM/CaM kinase II cascades. Expand
Characterization of the gene encoding both growth hormone-releasing hormone (GRF) and pituitary adenylate cyclase-activating polypeptide (PACAP) in the zebrafish
TLDR
Evidence that a duplication of the PACAP gene gave rise to the vasoactive intestinal peptide (VIP) gene is supported by the high amino acid sequence identity between PACAP in zebrafish and VIP in other fish species. Expand
Molecular Cloning of Growth Hormone-Releasing Hormone/Pituitary Adenylyl Cyclase-Activating Polypeptide in the Frog Xenopus laevis: Brain Distribution and Regulation after Castration1†.
TLDR
The castration-induced alterations of mRNA expression for PACAP and its selective type I receptor (PAC1) in the hypothalamic anterior preoptic area were analyzed and deduced peptide sequence of PACAP-38 was nearly identical to that of human PACAP with one amino acid substitution. Expand
Expression and alternative processing of a chicken gene encoding both growth hormone-releasing hormone and pituitary adenylate cyclase-activating polypeptide.
TLDR
The present evidence in chicken suggests a gene duplication in stem mammals, and it is determined that juvenile chicken mRNA encoding GRF is expressed in the brain and gonads, but not in the pituitary, heart, liver, kidney, crop, small intestine, large intestine, eye, and muscle. Expand
Sequence and expression of a cDNA encoding both pituitary adenylate cyclase activating polypeptide and growth hormone-releasing hormone-like peptide in channel catfish (Ictalurus punctatus).
TLDR
This study is the first to demonstrate mRNA expression of the GHRHLP/PACAP gene in fat or skeletal muscle of fish, and developed essential tools to investigate the roles of these peptides in the regulation of catfish growth. Expand
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