Growth-associated protein43 (GAP43) is a biochemical marker for the whole period of fish optic nerve regeneration.

@article{Kaneda2010GrowthassociatedP,
  title={Growth-associated protein43 (GAP43) is a biochemical marker for the whole period of fish optic nerve regeneration.},
  author={Manabu Kaneda and Mikiko Nagashima and Kazuhiro Mawatari and Tomoya Nunome and Kenichiro Muramoto and Kayo Sugitani and Satoru Kato},
  journal={Advances in experimental medicine and biology},
  year={2010},
  volume={664},
  pages={97-104}
}
In adult visual system, goldfish can regrow their axons and fully restore their visual function even after optic nerve transection. The optic nerve regeneration process in goldfish is very long and it takes about a half year to fully recover visual function via synaptic refinement. Therefore, we investigated time course of growth-associated protein 43 (GAP43) expression in the goldfish retina for over 6 months after axotomy. In the control retina, very weak immunoreactivity could be seen in the… CONTINUE READING

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