Growth arrest specific 1 (Gas1) and glial cell line-derived neurotrophic factor receptor α1 (Gfrα1), two mouse oocyte glycosylphosphatidylinositol-anchored proteins, are involved in fertilisation.

@article{Agopiantz2016GrowthAS,
  title={Growth arrest specific 1 (Gas1) and glial cell line-derived neurotrophic factor receptor α1 (Gfrα1), two mouse oocyte glycosylphosphatidylinositol-anchored proteins, are involved in fertilisation.},
  author={Mika{\"e}l Agopiantz and L Xandre-Rodriguez and Bin Jin and G Urbistondoy and C{\^o}me Ialy-Radio and Myriam Chalbi and J P Wolf and Ahmed Ziyyat and Brigitte Lef{\`e}vre},
  journal={Reproduction, fertility, and development},
  year={2016},
  volume={29 4},
  pages={824-837}
}
Recently, Juno, the oocyte receptor for Izumo1, a male immunoglobulin, was discovered. Juno is an essential glycosylphosphatidylinositol (GIP)-anchored protein. This result did not exclude the participation of other GIP-anchored proteins in this process. After bibliographic and database searches we selected five GIP-anchored proteins (Cpm, Ephrin-A4, Gas1, Gfra1 and Rgmb) as potential oocyte candidates participating in fertilisation. Western blot and immunofluorescence analyses showed that only… CONTINUE READING

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GDNF family

  • M. S. Airaksinen, A. Titievsky, M. Saarma
  • 1999
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