Growth arrest associated changes of mRNA levels in breast cancer cells measured by semi-quantitative RT-PCR: potential early indicators of treatment response.

Abstract

To find early and sensitive indicators of treatment response in breast cancer, we studied the mRNA levels of proliferation-related genes during growth arrest of the human breast cancer cell lines T47D and MCF7. A sensitive reverse transcriptase-PCR (RT-PCR) technique was used in order to monitor gene expression in small samples of cells. Estrogen-depletion… (More)

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@article{Maas1995GrowthAA, title={Growth arrest associated changes of mRNA levels in breast cancer cells measured by semi-quantitative RT-PCR: potential early indicators of treatment response.}, author={Riks A. Maas and Peter F. Bruning and Bert Top and Annette Breedijk and Hans L. Peterse}, journal={Cancer letters}, year={1995}, volume={97 1}, pages={107-16} }