Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster

@article{Domnguez2004GrowthAS,
  title={Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster},
  author={Mario S{\'a}nchez Dom{\'i}nguez and Dolors Ferr{\'e}s-Marc{\'o} and Francisco Jos{\'e} Guti{\'e}rrez-Avi{\~n}{\'o} and Stephan A Speicher and Monica Beneyto},
  journal={Nature Genetics},
  year={2004},
  volume={36},
  pages={31-39}
}
Control of growth determines the size and shape of organs. Localized signals known as 'organizers' and members of the Pax family of proto-oncogenes are both elements in this control. Pax proteins have a conserved DNA-binding paired domain, which is presumed to be essential for their oncogenic activity. We present evidence that the organizing signal Notch does not promote growth in eyes of D. melanogaster through either Eyeless (Ey) or Twin of eyeless (Toy), the two Pax6 transcription factors… CONTINUE READING
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