Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice.

@article{Naito1986GrowthAM,
  title={Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice.},
  author={Shinsaku Naito and Andrew C. von Eschenbach and Raffaella Giavazzi and Isaiah Josh Fidler},
  journal={Cancer research},
  year={1986},
  volume={46 8},
  pages={
          4109-15
        }
}
The purpose of this study was to determine whether the methods for isolating tumor cells from a human renal cell carcinoma (HRCC) influence the biological behavior of the cancer cells. Renal cell carcinoma obtained from a surgical specimen was dissociated by enzymatic treatment and cells were plated into culture dishes or injected s.c. into the kidney of BALB/c nude mice. The resultant kidney tumor produced liver metastasis and ascites. All tumors growing in nude mice (s.c., kidney, liver… CONTINUE READING

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