Growth and differentiation of a human megakaryoblastic cell line, CMK.

@article{Komatsu1989GrowthAD,
  title={Growth and differentiation of a human megakaryoblastic cell line, CMK.},
  author={Norio Komatsu and Toshio Suda and Masaaki Moroi and N Tokuyama and Yasuhiko Sakata and Masayuki Okada and Teruo Nishida and Yohei Hirai and Takeyuki Sato and Akira Fuse},
  journal={Blood},
  year={1989},
  volume={74 1},
  pages={42-8}
}
Recently, a human megakaryoblastic cell line, CMK, was established from the peripheral blood of a megakaryoblastic leukemia patient with Down syndrome. Using this cell line, we studied the proliferation and differentiation of megakaryocytic cells in the presence of highly purified human hematopoietic factors and phorbol 12-myristate-13-acetate (PMA). In a… CONTINUE READING