Growth and differentiation factor 11 (GDF11): Functions in the regulation of erythropoiesis and cardiac regeneration.

@article{Rochette2015GrowthAD,
  title={Growth and differentiation factor 11 (GDF11): Functions in the regulation of erythropoiesis and cardiac regeneration.},
  author={Luc Rochette and Marianne Zeller and Yves Cottin and Catherine Vergely},
  journal={Pharmacology & therapeutics},
  year={2015},
  volume={156},
  pages={26-33}
}
Members of the TGF-β superfamily transduce their signals through type I and II receptor serine/threonine kinases. The regulation of members of the TGF-β family is known to be complex, because many proteins able to bind the ligands and inhibit their activities have been identified. Growth and differentiation factor 11 (Gdf11) as activins belong to the TGF-β family. GDF11, like other members of the TGF-β superfamily, is produced from precursor proteins by proteolytic processing. The binding of… CONTINUE READING
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