Growth and development in thalassaemia major patients with severe bone lesions due to desferrioxamine

@article{Sanctis1996GrowthAD,
  title={Growth and development in thalassaemia major patients with severe bone lesions due to desferrioxamine},
  author={Vincenzo De Sanctis and Andrea Pinamonti and Antonella Marta Di Palma and Monica Sprocati and G. Atti and Maria Rita Gamberini and Calogero Vullo},
  journal={European Journal of Pediatrics},
  year={1996},
  volume={155},
  pages={368-372}
}
Nine transfusion-dependent β-thalassaemia major patients (seven males and two females), aged 4–15 years, with growth retardation and severe rickets-like radiological lesions due to continuous subcutaneous chelation therapy with desferrioxamine (45–75 mg/kg body weight, 6–7 times/week), were seen in our centre during the last 8 years. Serum ferritin levels ranged from 976 to 4115 μg/l. There was a progressive decline in growth velocity in these patients 2–3 years before the appearance of rickets… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 19 REFERENCES

Effect of different treatment regimes on linear growth and final height in ~ - thalassaemia major

V DeSanctis, M Katz, +3 authors B Wonke
  • Clin Endocrinol
  • 1994

Growth failure and bony changes induced by deferoxamine.

  • The American journal of pediatric hematology/oncology
  • 1992

Velocit~t di crescita dei bambini talassemici sottoposti a diversi protocolli di terapia chelante

MG Elena, A Fedele, +4 authors S Vanelli
  • Pediatr
  • 1992

Desferrioxamine induced bone dysplasia in patients with thalassaemia major

PW Brill, P Winchester, PI Giardina, S Cunnigham-Rundles
  • A J R
  • 1991
VIEW 3 EXCERPTS

Desfer - rioxamine ototoxicity : evaluation of risk factors in thalassemic patients and guidelines for safe dosage

JB Porter, MS Jaswon, ER Huhens, CA East, WP Jonathan
  • Br J Haematol
  • 1989

Desferrioxamine-induced growth retardation in patients with thalassemia major

S De Virgilis, M Congia, +9 authors A Cao
  • J Pediatr
  • 1988
VIEW 3 EXCERPTS