Growth Factor Variation in Two Types of Autologous Platelet Biomaterials: PRP Versus PRF.

Abstract

Autologous platelet biomaterials represent a key source of cytokines and growth factors extensively used for clinical and surgical applications involving tissue regeneration; wound healing and tissue repair. In this communication we discuss the growth factors released by activated platelet rich plasma (PRP) and platelet rich fibrin (PRF) releasate. Our study highlights that significantly higher growth factors (TGF-ß1) are released by activated PRP as compared to releasate of PRF. The various growth factors released by both platelet products are significantly higher than the baseline concentration in the whole blood and have different bio-mechanism hence should be individualized as per the clinical indication.

DOI: 10.1007/s12288-016-0721-8

Cite this paper

@article{Arora2017GrowthFV, title={Growth Factor Variation in Two Types of Autologous Platelet Biomaterials: PRP Versus PRF.}, author={Satyam Arora and Urvershi Kotwal and Mitu Dogra and Veena Doda}, journal={Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion}, year={2017}, volume={33 2}, pages={288-292} }