Growth Factor Stimulation Improves the Structure and Properties of Scaffold-Free Engineered Auricular Cartilage Constructs

@inproceedings{Rosa2014GrowthFS,
  title={Growth Factor Stimulation Improves the Structure and Properties of Scaffold-Free Engineered Auricular Cartilage Constructs},
  author={Renata Giardini Rosa and Paulo Pinto Joazeiro and Juares Ednaldo Romero Bianco and Manuela Kunz and Joanna F. Weber and Stephen D. Waldman},
  booktitle={PloS one},
  year={2014}
}
The reconstruction of the external ear to correct congenital deformities or repair following trauma remains a significant challenge in reconstructive surgery. Previously, we have developed a novel approach to create scaffold-free, tissue engineering elastic cartilage constructs directly from a small population of donor cells. Although the developed constructs appeared to adopt the structural appearance of native auricular cartilage, the constructs displayed limited expression and poor… CONTINUE READING

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