Growth Effects of Vanadium in the Rat

  title={Growth Effects of Vanadium in the Rat},
  author={Klaus Schwarz and David Bayard Milne},
  pages={426 - 428}
Vanadium is necessary for growing rats raised inside trace elementcontrolled, all plastic isolators on a highly purified amino acid diet. Addifion of vanadium to the diet enhances growth by over 40 percent. A nearly optimum effect is obtained with 10 micrograms of vanadium per 100 grams of diet in (0.1 part per million), supplied in the form of sodium orthovanadate, as seen from series of tests with levels ranging from 1 to 5 micrograms per 100 grams of diet. Different vanadium compounds show… 
Is vanadium of human nutritional importance yet?
Effects of dietary vanadium in mallard ducks.
Vanadium concentrations in most tissues were significantly correlated and increased with treatment level, suggesting an interaction between vanadium and calcium mobilization in laying hens.
Balance and tissue distribution of vanadium after short-term ingestion of vanadate.
Values indicate greater absorption and retention of ingested vanadium than found in previously reported investigations, and suggest that polyuria induced in animals on the high potassium diets may be reversed.
The Essentiality and Metabolism of Vanadium
The hypothesis that vanadium is nutritionally essential for higher animals, including humans, has had a long and checkered history and the conclusion of Schroeder et al., (1963) that “no other trace metal has so long had so many supposed biological activities without having been proved to be essential” has begun to crumble.
Growth-promoting Effects of Silicon in Rats
An all-plastic trace element controlled isolator system has been created and it was able to demonstrate recently that tin3,4, vanadium5, and fluorine6 (K. S. and D. M., unpublished results) are essential for growth.
The biochemistry of vanadium
There is ample evidence that vanadium in the body exists primarily as the vanadyl(IV) ion, VO2+, complexed to proteins and other cellular components; several biological reducing agents can convert vanadium(V) to this form.
Interactions among vanadium, iron, and cystine in rats growth, blood parameters, and organ Wt/body Wt ratios
The findings indicated that vanadium neither substitutes for iron at some metabolic site, nor stimulates iron absorption; but has a positive influence on the utilization of iron after absorption.


Effect of Ingested Vanadium on Cholesterol and Phospholipid Metabolism in the Rabbit.∗
Summary Vanadium, in the form of vanadium pentoxide, added to a standard diet, at a level of 100 ppm of the element lowered free cholesterol ancl phospholipid content of the liver of rabbits, while
Vanadium, a Caries-Inhibiting Trace Element in the Syrian Hamster
  • C. Geyer
  • Chemistry
    Journal of dental research
  • 1953
A thorough study of these elements resulted in the conclusion that vanadium might be able to increase the resistance of the tooth to caries if it were present in sufficient quantities in the dentin and enamel.
Vanadium Catalysis of the Oxidation of Catechol Amines, Dihydroxyphenylalanine and 5-Hydroxyindoles
An investigation of the mechanism of enzymatic oxidation of serotonin by human serum found that apparently identical chromatographic reaction products resulted when this oxidation was catalysed non-enzymatically by cupric ion, and became curious as to what extent transitional metals other than copper catalysed this reaction.
The chemistry of titanium and vanadium.